Clorprenaline

Clorprenaline
Clinical data
Other namesChlorprenaline; Isoprophenamine; Compound 20025; L-20025; 2-Chloro-β-hydroxy-N-isopropylphenethylamine
Drug classSympathomimetic; Bronchodilator; Sympathomimetic
Identifiers
IUPAC name
  • 1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.021.175
Chemical and physical data
FormulaC11H16ClNO
Molar mass213.71 g·mol−1
3D model (JSmol)
SMILES
  • CC(C)NCC(C1=CC=CC=C1Cl)O
InChI
  • InChI=1S/C11H16ClNO/c1-8(2)13-7-11(14)9-5-3-4-6-10(9)12/h3-6,8,11,13-14H,7H2,1-2H3
  • Key:SSMSBSWKLKKXGG-UHFFFAOYSA-N

Clorprenaline (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name), also known as isoprophenamine and known as clorprenaline hydrochloride (USANTooltip United States Adopted Name, JANTooltip Japanese Accepted Name) in the case of the hydrochloride salt, is a sympathomimetic and bronchodilator medication which is marketed in Japan.[1][2][3] It acts as a β-adrenergic receptor agonist or as a β-sympathomimetic.[2][3] Brand names of clorprenaline in Japan are numerous and include Asnormal, Bazarl, Bronchon, Clopinerin, Conselt, Cosmoline, Fusca, Kalutein, Pentadoll, Restanolon, and Troberin.[2][1] The drug was first described in the literature by 1956.[1][4]

References

  1. 1 2 3 Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 305. ISBN 978-1-4757-2085-3. Retrieved 17 October 2024.
  2. 1 2 3 Schweizerischer Apotheker-Verein (2004). Index Nominum: International Drug Directory. Medpharm Scientific Publishers. p. 309. ISBN 978-3-88763-101-7. Retrieved 17 October 2024.
  3. 1 2 Morton IK, Hall JM (2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. p. 80. ISBN 978-94-011-4439-1. Retrieved 17 October 2024.
  4. ↑ Gibson WR, Powell CE, Swanson EE (December 1956). "The pharmacological action of 1-o-chlorophenyl-2-isopropylaminoethanol (isoprophenamine); a bronchodilator". J Am Pharm Assoc. 45 (12): 785–787. doi:10.1002/jps.3030451205. PMID 13376372.


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