The Shulgin Index

The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds
AuthorAlexander Shulgin, Tania Manning, and Paul F. Daley
LanguageEnglish
SubjectPharmacology; Chemistry; Psychoactive drugs; Phenethylamines; Psychedelics
PublisherTransform Press
Publication date
2011
Publication placeUnited States
Media typeHardcover
Pages811
ISBN978-0963009630
OCLC709667010
TextThe Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds at Internet Archive
Websitehttps://transformpress.com/publications/

The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds is a 2011 book written by Alexander Shulgin, Tania Manning, and Paul F. Daley and published by Transform Press.[1][2][3] It followed the earlier books PiHKAL: A Chemical Love Story (1991) and TiHKAL: The Continuation (1997) by Shulgin and his wife Ann Shulgin.[1][2][4][5] The book is about psychedelic substituted phenethylamines and related compounds and their chemistry and pharmacology.[1][2][3] It discusses 126 main compounds from this family as well as 1,300 compounds discussed in total.[1][3]

A second volume on substituted tryptamines was being prepared but was never completed due to Shulgin's death in 2014.[1][6][7] According to the Multidisciplinary Association for Psychedelic Studies (MAPS) in 2014 however, the second volume would be finished at some point in the near future.[7]

Compounds listed

#CompoundIUPAC NameLink
1AEM (α-ethylmescaline)α-Ethyl-1-(3,4,5-trimethoxyphenyl)ethylamine
2AL (allylescaline)4-Allyloxy-3,5-dimethoxyphenethylamine
3ALEPH2,5-Dimethoxy-4-methylthioamphetamine
4ALEPH-22,5-Dimethoxy-4-ethylthioamphetamine
5ALEPH-42,5-Dimethoxy-4-(i)-propylthioamphetamine
6ALEPH-72,5-Dimethoxy-4-propylthioamphetamine
7ARIADNE2,5-Dimethoxy-4-methyl-α-ethylphenethylamine
8ASB (asymbescaline)3,4-Diethoxy-5-methoxyphenethylamine
9BDBα-Ethyl-3,4-methylenedioxyphenethylamine
10B-DFLY (Bromo-DragonFLY)1-(8-Bromobenzo [1,2-b;4,5-b']difuran-4-yl)-2-aminopropane
11BEATRICE2,5-Dimethoxy-N,4-dimethylamphetamine
12B-FLY (DOB-FLY)1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)-2-aminopropane
13BOB4-Bromo-β,2,5-trimethoxyphenethylamine
14BOD4-Methyl-2,5,β-trimethoxyphenethylamine
15BOHβ-Methoxy-3,4-methylenedioxyphenethylamine
16BOMβ,3,4,5-Tetramethoxyphenethylamine
17B-SF1-(7-Bromo-5-methoxy-2,3-dihydrobenzofuran-4-yl)-2-aminopropane
182C-B4-Bromo-2,5-dimethoxyphenethylamine
192C-C4-Chloro-2,5-dimethoxyphenethylamine
202C-D2,5-Dimethoxy-4-methylphenethylamine
212C-E2,5-Dimethoxy-4-ethylphenethylamine
222C-H2,5-Dimethoxyphenethylamine
232C-I2,5-Dimethoxy-4-iodophenethylamine
24mCPP1-(3-Chlorophenyl)piperazine
252C-T2,5-Dimethoxy-4-methylthiophenethylamine
262C-T-22,5-Dimethoxy-4-ethy lthiophenethylamine
272C-T-72,5-Dimethoxy-4-(n)-propylthiophenethylamine
282C-TFM2,5-Dimethoxy-4-trifluoromethylphenethylamine
29DESMETHYL (4-desmethylmescaline)3,5-Dimethoxy-4-hydroxyphenethylamine
303-DESMETHYL (3-desmethylmescaline)3,4-Dimethoxy-5-hydroxyphenethylamine
31DESOXY (4-desoxymescaline)3,5-Dimethoxy-4-methylphenethylamine
32DFLY (DragonFLY)1-(Benzo[1,2-b:4,5-b']difuran-4-yl)-2-aminopropane
33DHA (α-methyldopamine)3,4-Dihydroxyamphetamine
342,3-DMA2,3-Dimethoxyamphetamine
352,4-DMA2,4-Dimethoxyamphetamine
362,5-DMA2,5-Dimethoxyamphetamine
372,6-DMA2,6-Dimethoxyamphetamine
38DMA3,4-Dimethoxyamphetamine
393,5-DMA3,5-Dimethoxyamphetamine
40DMAP (metamfepramone)2-Dimethylaminopropiophenone
41DMCPA4-Methyl-2,5-methoxycyclopropylamine
42DMeA (xylopropamine)3,4-Dimethylamphetamine
43DMePEA3,4-Dimethylphenethylamine
44DMMDA2,5-Dimethoxy-3,4-methylenedioxyamphetamine
45α,N-DMMDBA (MDM1EA)α,N-Dimethyl-3,4-methylenedioxybenzylamine
462,3-DMPEA2,3-Dimethoxyphenethylamine
472,4-DMPEA2,4-Dimethoxyphenethylamine
482,6-DMPEA2,6-Dimethoxyphenethylamine
49DMPEA3,4-Dimethoxyphenethylamine
503,5-DMPEA3,5-Dimethoxyphenethylamine
51DOAM4-Amyl-2,5-dimethoxyamphetamine
52DOB4-Bromo-2,5-dimethoxyamphetamine
53DOBU4-Butyl-2,5-dimethoxyamphetamine
54DOC4-Chloro-2,5-dimethoxyamphetamine
55DOCN4-Cyano-2,5-dimethoxyamphetamine
56DOET2,5-Dimethoxy-4-ethylamphetamine
57DOF2,5-Dimethoxy-4-fluoroamphetamine
58DOI2,5-Dimethoxy-4-iodoamphetamine
59DOIP2,5-Dimethoxy-4-isopropylamphetamine
60DOM2,5-Dimethoxy-4-methylamphetamine
61DON2,5-Dimethoxy-4-nitroamphetamine
62DOPR2,5-Dimethoxy-4-propylamphetamine
63DOTFM2,5-Dimethoxy-4-trifluoromethylamphetamine
64Escaline3 ,5-Dimethoxy-4-ethoxyphenethylamine
65EDA3,4-Ethylenedioxyamphetamine
66F (semi-fly)1-(5-Methoxy-2,3-dihydrobenzofuran-6-yl)-2-aminopropane
67FEA2-Furylethylamine
68FLY1-(2,3,6,7-Tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)-2-aminopropane
69GEA (3-methoxytyramine)4-Hydroxy-3-methoxyphenethylamine
70HMePEA (N-methyltyramine)4-Hydroxy-N-methylphenethylamine
71HordenineN,N-Dimethyl-4-hydroxyphenethylamine
72IM (isomescaline)2,3,4-Trimethoxyphenethylamine
73Lophophine3-Methoxy-4,5-methylenedioxyphenethylamine
742-MA2-Methoxyamphetamine
753-MA3-Methoxyamphetamine
76MBDBα-Ethyl-N-methyl-1,3-benzodioxole-5-ethanamine
77MDA3,4-Methylenedioxyamphetamine
78homo-MDA1-(3,4-Methylenedioxylphenyl)-3-isobutylamine
79MDBP (MDBZP)1-(3,4-Methylenedioxybenzyl)piperazine
80MDDMA3,4-Methylenedioxy-N,N-dimethylamphetamine
81MDE (MDEA)N-Ethyl-3,4-methylenedioxyamphetamine
82MDMA3,4-Methylenedioxymethamphetamine
83homo-MDMAN-Methyl-1-(3,4-methylenedioxyphenyl)-3-isobutylamine
84MDOHN-Hydroxy-3,4-methylenedioxyamphetamine
85MDPEA3,4-Methylenedioxyphenethylamine
86MDPR3,4-Methylenedioxy-N-propylamphetamine
87MEM2,5-Dimethoxy-4-ethoxyamphetamine
88MeOPP (pMeOPP)1-(4-Methoxyphenyl)piperazine
89N-MePEAN-Methylphenethylamine
90MEPEA3-Methoxy-4-ethoxyphenethylamine
91Mescaline3,4,5-Trimethoxyphenethylamine
92METHCATH (methcathinone)β-Keto-N-methylamphetamine
93Methylone3,4-Methylenedioxymethcathinone
94MHA (HMA)3-Methoxy-4-hydroxyamphetamine
95M-M (N-methylmescaline)N-Methyl-3,4,5-trimethoxyphenethylamine
963,4-MMA (MMA)3-Methoxy-4-methylamphetamine
97MMDA3-Methoxy-4,5-methylenedioxyamphetamine
98MMDA-22-Methoxy-4,5-methylenedioxyamphetamine
99MMDA-3a2-Methoxy-3,4-methylenedioxyamphetamine
1002-MPEA2-Methoxyphenethylamine
1013-MPEA3-Methoxyphenethylamine
1024-MPEA4-Methoxyphenethylamine
103MTA (4-MTA)4-Methylthioamphetamine
104Proscaline3,5-Dimethoxy-4-propoxyphenethylamine
105PAT (8-OH-DPAT)8-Hydroxy-2-(dipropylamino)tetralin
106PCA (4-CA)4-Chloroamphetamine
107PEA (phenethylamine)2-Phenylethylamine
108PeMPEA2,3,4,5,6-Pentamethoxyphenethylamine
109PHA (norpholedrine)4-Hydroxyamphetamine
110PMA4-Methoxyamphetamine
111PMeA (4-MA)4-Methylamphetamine
112PMMA4-Methoxy-N-methylamphetamine
113TeMA2,3,4,5-Tetramethoxyamphetamine
114TeMPEA2,3,4,5-Tetramethoxyphenethylamine
115TeMPEA-32,3,5,6-Tetramethoxyphenethylamine
116mTFMPP (TFMPP)1-(3-(Trifluoromethyl)phenyl)piperazine
117TMA3,4,5-Trimethoxyamphetamine
118TMA-22,4,5-Trimethoxyamphetamine
119TMA-32,3,4-Trimethoxyamphetamine
120TMA-42,3,5-Trimethoxyamphetamine
121TMA-52,3,6-Trimethoxyamphetamine
122TMA-62,4,6-Trimethoxyamphetamine
123TMePEA3,4,5-Trimethylphenethylamine
124TMPEA-22,4,5-Trimethoxyphenethylamine
125TrichocereineN,N-Dimethyl-3,4,5-trimethoxyphenethylamine
126Tyramine4-Hydroxyphenethylamine

References

  1. 1 2 3 4 5 Sumnall HR, Evans-Brown M, McVeigh J (2011). "Social, policy, and public health perspectives on new psychoactive substances". Drug Test Anal. 3 (7–8): 515–523. doi:10.1002/dta.310. PMID 21744515. Shulgin's PIHKAL[25] and TIHKAL[26] describe synthesis routes and basic human psychopharmacology of many potential hallucinogenic and entactogenic compounds [...] The Shulgin Index Volume 1, Psychedelic Phenethylamines and Related Compounds (to be followed by a similar volume on tryptamines) was published in 2011,[119] providing a focused, fully referenced examination of the chemistry and pharmacology of 126 compounds, many of them new.
  2. 1 2 3 Francis, Arie P.; Smith, Silas W. (2022). "Availability and supply of novel psychoactive substances". Novel Psychoactive Substances. Elsevier. pp. 57–84. doi:10.1016/b978-0-12-818788-3.00001-2. ISBN 978-0-12-818788-3. [Novel psychoactive substance (NPS)] development and manufacturing efforts are aided by those with scientific training who develop or scan research literature for novel structures or derivatives [59]. Substituted phenethylamines and tryptamines were explicitly described in the 1990s by synthetic chemist Alexander Shulgin in the books PiHKAL and TiHKAL, which maintain an online presence [101,102]. The Shulgin Index, cataloguing psychedelic phenethylamines, amphetamines, phenylpiperazines, and others, including synthesis and pharmacological properties, was released in 2011 [103].
  3. 1 2 3 Shulgin, A.; Manning, T.; Daley, P.F. (2011). The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley: Transform Press. ISBN 978-0-9630096-3-0. Retrieved 2 November 2024. The Shulgin Index is a comprehensive collection of the known psychedelic phenethylamines and related compounds. There are 126 main compounds with detailed physical properties, synthesis and analytical chemistry, biochemistry, pharmacological properties, and legal status. Fully referenced with over 2,000 citations. There are sub-tables of lesser-studied structural homologues and analogues, over 1300 total compounds covered. GCMS scans are included for 229 compounds. This book is an invaluable resource for researchers, physicians, chemists, and law enforcement.
  4. Shulgin, A.T.; Shulgin, A. (1991). PiHKAL: A Chemical Love Story. Transform Press. ISBN 978-0-9630096-0-9. Retrieved 2 November 2024.
  5. Shulgin, A. (1997). TiHKAL: The Continuation. Transform Press. ISBN 978-0-9630096-9-2. Retrieved 2 November 2024.
  6. Weber, Bruce (7 June 2014). "Alexander Shulgin, Psychedelia Researcher, Dies at 88". The New York Times. Retrieved 3 November 2024.
  7. 1 2 Multidisciplinary Association for Psychedelic Studies (Summer 2014). "In Memoriam: Alexander "Sasha" Shulgin, Ph.D. (June 17, 1925–June 2, 2014)" (PDF). MAPS Newsletter. 24 (2): 9–12 (11). ON JUNE 2, 2014, AT THE age of 88, pioneering psychedelic researcher Alexander "Sasha" Shulgin died surrounded by friends and family at his home in Lafayette, California. [...] In 2011, his life's work was published in The Shulgin Index, Volume 1: Psychedelic Phenethylamines and Related Compounds. While the first volume contains over 1,300 compounds, there is more to come. The Shulgin Index, Volume 2 will be published in the near future. Sasha understood that the exploration of novel psychoactive compounds—and ways to use them—would not be completed in his lifetime, so he preserved his research in these volumes for future generations.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.