I first thought that the answer to this question was a definite 'yes.' The target is "A creature of your choice that you can see within range" (PHB 250). Presumably the caster is a creature, can be seen by him/herself, and is within range of 60' of him/herself.
Then I read the description for Greater Invisibility which specifies "You or a creature you touch becomes invisible until the spell ends" (PHB 246). It seems that Wizards have emphasized that Greater Invisibility can be applied to oneself while the same option is not emphasized for Healing Word.
Am I to interpret the lack of a specific option to heal oneself as meaning Healing Word cannot target self?
Bonus question: does this apply to Cure Wounds (PHB 230) as well?