I have a question about Granger causality with a specific dataset.
Let's say I give 50 mice some treatment and I am interested in seeing how gene expression in the heart changes over 5 days. Since I have to harvest the heart in order to test gene expression, I test it in 10 mice every day.
Now I don't have a true time series because the genes measured on day 1 are from a different sample of mice than genes measured from day 2.
Can I still do Granger Causality on this dataset? Can I just take the mean expression at each day?
Thank You!
Vitaly