Bridging integrator 2

BIN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4AVM, 4I1Q
Identifiers
Aliases	BIN2, BRAP-1, bridging integrator 2
External IDs	OMIM: 605936; MGI: 3611448; HomoloGene: 22965; GeneCards: BIN2; OMA:BIN2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	51,324,668 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	100,567,434 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; blood; ; bone marrow cells; ; spleen; ; trabecular bone; ; lymph node; ; appendix; ; right lung; ; upper lobe of left lung;
	Top expressed in
	granulocyte; ; secondary oocyte; ; spleen; ; thymus; ; primary oocyte; ; placenta; ; zygote; ; bone marrow; ; yolk sac; ; testicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phospholipid binding;
Cellular component	cytoplasm; podosome; cell junction; plasma membrane; cell projection; cell cortex; phagocytic cup; membrane; extracellular region; secretory granule lumen; ficolin-1-rich granule lumen;
Biological process	cell chemotaxis; podosome assembly; phagocytosis, engulfment; plasma membrane tubulation; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	51411
	668218
	ENSG00000110934
	ENSMUSG00000098112
	Q9UBW5
	D3Z6Q9
NM_001290007; NM_001290008; NM_001290009; NM_016293; NM_001364779;
	NM_001364780; NM_001364781
	NM_001270537; NM_001368666
NP_001276936; NP_001276937; NP_001276938; NP_057377; NP_001351708;
	NP_001351709; NP_001351710
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Bridging integrator 2 is a protein that in humans is encoded by the BIN2 gene. ^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000110934 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000098112 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Bridging integrator 2". Retrieved 2018-05-10.

PDBe-KB provides an overview of all the structure information available in the PDB for Human Bridging integrator 2

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