Urothelial papilloma

A urothelial papilloma is a rare, noncancerous tumor found within the urinary tract.

Clinical Presentation

The most common presenting symptom is hematuria (blood in urine). The average age at which it occurs is 46 years old.

Morphology and Histology

The tumor is made of a fibrovascular core covered by seemingly normal urothelium tissue. Under microscope, papillary (finger-like) fronds can be seen that feature occasional branching, but no fusion.

Genetic Associations

The tumors are diploid (contain two sets of chromosomes). They commonly show FGFR3 mutations.[1]

References

  1. ↑ "Pathology of Urinary Bladder Urothelial Papilloma: Definition, Clinical Features and Imaging, Gross and Microscopic Findings". 2023-12-19. {{cite journal}}: Cite journal requires |journal= (help)
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