Disseminated coccidioidomycosis

Disseminated coccidioidomycosis
Other namesCoccidioidal granuloma
Characteristic skin granulomata on the forehead.
SpecialtyInfectious diseases

Disseminated coccidioidomycosis is a systemic infection caused by Coccidioides immitis. 15-20% of people with the infection develop skin lesions.[1]: 315 

History of treatment

One of the earliest treatments for the disease was publicized in the New York State Journal of Medicine in 1959, in an article titled "Disseminated Coccidioidomycosis Treated with Amphotericin B". The case centered around a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Prior to the introduction of Amphotericin B, disseminated coccidioidomycosis had no specific chemotherapeutic treatment. Amphotericin B, a polyene antifungal antibiotic, was first trialed for this condition approximately three years earlier. Since then, multiple reports have highlighted the drug's clinical effectiveness in patients with coccidioidomycosis. [2]

See also

References

  1. ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ↑ La Barbera, M.D., Salvatore A. (October 1, 1959). "Disseminated Coccidioidomycosis Treated with Amphotericin B". New York State Journal of Medicine. 59 (19): 3644.
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