If you're using GNU find (as is used on most Linux systems), you'll want to use -mount:
find / -mount -name .vimrc
OS X/MacOS provides the local pseudo-fstype. This not in GNU find (fstypes recognized by GNU find).
Use the -fstype local option to find on MacOS:
find / -fstype local -name .vimrc
If you want to exclude only specific paths, you could use -prune:
find / -path "/path/to/ignore" -prune -o -name .vimrc
Update: MacOS Catalina (Jan 2022)
I'm two major releases behind the latest MacOS, but some has changed.
First, MacOS now supports the -mount option. The man page for find says "The same thing as -xdev, for GNU find compatibility."
Second, -fstype local still seems to work. The man page Indiates that it "matches any file system physically mounted on the system where the find is being executed".
I did a test with two drives mounted in /Volumes, one a USB flash drive (which I think counts as physically mounted) and the other a network drive. I ran find /Volumes <option> -name '*txt'. Running with -mount returned no results immediately since there were no such files on the current filesystem. Running with -fstype local found a .txt file on the USB drive very quickly and then seemed to traverse the full mounted drive without returning any files (even though some do exist).
findpipe togrepas shown in this answer: http://superuser.com/questions/80033/command-line-wizardry-spaces-in-file-names-with-find-grep-xargs/80050#80050 . Lately, I've been usingack(http://betterthangrep.com/) instead, butackdoesn't seem to have an option to search only local drives. – Doug Harris Jan 05 '11 at 15:43-pruneto it or it will still traverse the undesired file systems. The second example I believe was meant to be-pathinstead of-nameso it will ignore the path. FWIW... the last example does work, it stays on the "current filesystem" so doesn't traverse others. – rogerdpack Apr 16 '19 at 17:48findman page and submit an edit, I'd appreciate it. – Doug Harris Oct 13 '20 at 14:37