Statistical Analysis Stack Exchange
Statistical Analysis Stack Exchange

Questions tagged [biostatistics]

The science of statistics applied to the analysis of biological or medical data.

Biostatistics (sometimes referred to as biometry or biometrics) is the application of statistics to a wide range of topics in biology. The science of biostatistics encompasses the design of biological experiments, especially in medicine, agriculture and fishery; the collection, summarization, and analysis of data from those experiments; and the interpretation of, and inference from, the results. A major branch of this is medical biostatistics, which is exclusively concerned with medicine and health.

Reference: Wikipedia

Excerpt reference: thefreedictionary.com

1362 questions
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Which statistical test should be used to test for enrichment of gene lists?

I have performed an experiment to test the cellular sensitivity to a certain DNA damage agent. We have found 270 genes that were specifically sensitive to the drug and the total number of genes analyzed was 3668. 38 out of the 270 sensitive genes…
Laura
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What are the statistical reasons behind defining BMI index as weight/height$^2$?

Maybe this question has answer in medicine, but are there any statistical reasons why BMI index is calculated as $\text{weight}/\text{height}^2$? Why not for example just $\text{weight}/\text{height}$? My first idea is that it has something to do…
sitems
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Assessing the relationship between continuous variables

Age.of.Diagnosis Native.American European African 60 0.5 0.4 0.1 I have the ancestry data on ~100 individuals with cancer, and I would like to know how ancestry affects the age of diagnosis. Essentially I…
Adrian
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DNA exoneration: what are the chances?

As with any biometric, both the False Acceptance Rate (i.e. what is the chance that two samples of different individuals match) as well as the False Rejection Rate (i.e. what is the chance that two samples of the same individual do not match) are…
Michael
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Optimal analysis methodology for tracking effect of BLM protests on subsequent covid rates

I want to see if there is a correlation between BLM protests by time, place, and number of protesters with covid rates 1, 2, and 3 weeks from the date of the protest. The best methodology I could think of was essentially a case-control setup, where…
user1578295
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Controlled clinical trial, what is controlled refering to?

We say a (randomized) controlled clinical trial for a specific study design. Now my question is, what is controlled refering to? Different things come up to my mind: Controlled in the sense that the design and the process of the study is fixed…
biogu
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Is there a way to do Tukey's HSD test for the combined results of a one-way ANOVA and a two-way ANOVA? Or should both be followed by separate tables?

Tested the inhibitory effect of 2 essential oils on bacteria at 5 different concentrations. Thus, the first independent variable is the type of oil used and the second is the concentrations. A two-way ANOVA with replication (since I had 10 trials…
anonymous1924
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What statistical test can I run on data from an experiment with 1 independent variable and 2 dependent variables?

To specify my academic level, I am a high school student. For the lab report, I am required to conduct statistical tests to validate my results. What I had done was vary the concentration of an inhibitor (2%, 4%, 6%, 8%, 10%) and see how that…
anonymous1924
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Statistical comparison of mean protein expression data from imaging mass cytometry (single cell)

I acquired some protein expression data of one protein marker (e.g. CD45, expression range between 0-4, not necessarily integer and on a continuous scale) in a Control group and a Treated group. This is single cell imaging cell mass cytometry data,…
MeganCole
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What statistical test do you perform to compare sugar consumption between two groups of people?

I collected data from 10 patients regarding the amount of sugar they consume in a day and want to see whether this amount significantly differs from the average amount of sugar consumed by the general population per day. This value consumed by the…
Learner
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Statistical test for genomic distance

I'm hoping for some help with a problem that arose today. I have two groups measurements. A total of 200 blood samples from myeloid leukemia patients. 10 samples show mutations in a DNA binding protein that facilitates epigenetic modifiation of…
Matt
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What type of a test will I perform in R?

I have a dataset which contains data observed for patients who were hospitalized for moderate or severe infection and given one of two antibiotics. The number of days each patient was hospitalized before discharge was also noted down. The analysis…
saintacacia
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Programs and procedure for Blackwood test?

I am looking for programs and procedure for the Bradley-Blackwood test, which is normally used to assess test-retest reproducibility.
user39768
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Calculating the influence of each perturbation to a system, knowing the outcome of every possible combination of perturbations

I have generated structure predictions of a protein-protein interaction with different mutations at the interface. The outcome of a single mutation usually doesn't have an effect in this system, but having multiple mutations sensitizes it to have a…
chubs
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Biostatistics - How to evaluate a prognostic predictive model at 5 different year points?

So essentially I have patient data for a period of 5 years: same patient each year each person has 5 predicted risks (for each year) - e.g. in 2017 there risk was 2%, in 2018 the same patients risk was 8% etc The equation predicts the risk of an…
RazaS
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