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For a regression model where you are certain that y that depends on some predictors but are agnostic about whether some other predictors should enter, how should you incorporate this prior information? The elastic net approach penalizes a weighted sum of the absolute values and squared values of the regression coefficients, but you may want to penalize some coefficients more strongly than others. Has there been research on elastic net (or lasso or ridge) regression with uneven penalties for the predictors? I'm assuming that all predictors have been scaled to have zero mean and unit variance.

Richard Hardy
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