You can use the Otsu's method, you can think at your histogram as the histogram of the grey values of pixels in an image.
Then, in computer vision and image processing, Otsu's method, named after Nobuyuki Otsu (大津展之 Ōtsu Nobuyuki)1, is used to automatically perform clustering-based image thresholding, or, and that is your case, the reduction of a graylevel image to a binary image.
The algorithm assumes that the image contains two classes of pixels following bi-modal histogram (foreground pixels and background pixels), it then calculates the optimum threshold separating the two classes so that their combined spread (intra-class variance) is minimal, or equivalently (because the sum of pairwise squared distances is constant), so that their inter-class variance is maximal.
1Otsu, Nobuyuki. "A threshold selection method from gray-level histograms."
IEEE transactions on systems, man, and cybernetics 9.1 (1979): 62-66.