Say you have two possible different responses, $Y$ and $Z$, and they are in different units and have different ranges. Your covariates are $X_1$, $X_2$, and $X_3$. Model 1 uses $Y$ as the response, and $X_1$, $X_2$, and $X_3$ as the predictors. Model 2 uses $Z$ as the response, and $X_1$, $X_2$, and $X_3$ as the predictors.
How do you decide which predictive model is better after cross validation if you just need a good model and don't have a preference of $Y$ or $Z$ as the response? $MSE$ doesn't seem to be a good measure of fit after cross validation because it's unit dependent. Any other suggestions besides using cross validation?