If you mean rare events by the outcome variable having binary response where other has a very small frequency then it might be that frequency itself is not so important but number of cases. It might also be that there is not enought variation between response and levels of predictor categorical variables or in range of variation of continous predictor variables. If you do have this variation, it means that it is not possible to infer marginal effect of some variable to the outcome.
Firth penalized likelihood estimator can also be used, for example when having small amount of cases and possible some zero cells in multidimensional space when having categorical predictors.
http://cran.r-project.org/web/packages/logistf/logistf.pdf