You need to obtain a FieldInfo instance for the property's backing field and call the SetValue() method.
The Mono.Reflection library (available in Package Manager) will help you find the backing field.
If the Property is an auto-property, you can call the GetBackingField() extension method on the PropertyInfo instance.
Otherwise, you'll have to disassemble the IL of the MethodInfo of the getter like this:
var instructions = yourProp.GetGetMethod().GetInstructions();
This will give you a list of the method's IL instructions. If they look like this:
Ldarg0
Ldfld (Backing Field)
Ret
Then the 2nd Instruction will give you the backing field. In code:
if (instructions.Count == 3 && instructions[0].OpCode == OpCodes.Ldarg_0 && instructions[1].OpCode == OpCodes.Ldfld && instructions[2].OpCode == OpCodes.Ret)
{
FieldInfo backingField = (FieldInfo)instructions[1].Operand;
}
Otherwise, the property is probably computed and has no backing field.