After doing some research, I've found that most of the literature on operator splitting methods (e.g. Strang Splitting, Fractional Step, etc.) are specifically designed for a standard problem type of the form:
$$u'=(A+B)u.$$
In my application, I have a slightly different form:
$$Mu'=(A+B)u$$
where $M$ is not the identity operator. Can the same methodologies be applied when an operator is applied to the $u'$ term? Are there any other numerical methods to handle this case specific case there $M$ is not the identity operator? In particular, I'm looking at a case where $M$ is singular.
Update
To put my particular problem into greater context, my operator is
$$M=\left[\begin{array}{cc} 0 & 0 \\ I & I\end{array}\right]$$
and
$$u=\left[\begin{array}{c} u_1 \\ u_2 \end{array}\right]$$