Surprisingly it is not best to play in the corner but near a corner. The corners do not give you enough information to proceed. Near the corner helps eliminate one possible 50% guess.
I have written a solver for MineSweeper and the odds of winning are posted below based on the size of the puzzle. The coordinates such as (x,y) assumes the upper left corner is (0,0) and the array references are puzzle[y][x]. Each result used 200,000 samples. Anything less than this leads to misconceptions because the standard deviation is so large. I am not finished so it is possible these odds could increase.
Size Pos Percent Estimated deviation
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small 2,2 96.955% .04%
small 2,1 96.919% .04%
small 3,2 96.886% .04%
small 3,3 96.671% .04%
medium 3,2 87.683% .08%
medium 2,2 87.618% .08%
medium 3,3 87.541% .08%
expert 3,3 46.916% .11%
expert 3,2 46.833% .11%
I will be posting the source source code soon probably on GitHub.