3,932,156 points over 18.2 hours @ 1 move / second
Let's assume 1 move / second and all thanks to Reddit
This assumes that every tile you spawn is a 2, and the last tile you spawn is a 4.
There are $16$ squares. You'd think that the highest possible number would be $2
^{16} (=65536)$, which would fill up the board, making it impossible to progress. However, if you do manage to spawn a 4 tile as your last tile, then you can continue to progress to $2^{17} (=131,072)$.
Scoring works like this:
Merging two lower-tier blocks together will give you the score of the higher-tier block (score of $+8$ gained from merging two 4s). For any specific tile score, you have to add up all the scores from the lower tiers.
- Creating a 2 tile $= +0$ pts
- Creating a 4 tile $= 4 = +4$ pts
- Creating an 8 tile $= 8 + (2\times4) = +16$ pts
- Creating a 16 tile $= 16 + (2\times8) + (4\times4) = +48$ pts
- Creating a 32 tile $ = 32 + (2\times16) + (4\times8) + (8\times4) = +128$ pts ...
Which can be simplified:
- Tile $2^1$$ = 0 \times 2^1 = 0$ pts
- Tile $2^2$$ = 1 \times 2^2 = 4$ pts
- Tile $2^3$$ = 2 \times 2^3 = 16$ pts
- Tile $2^4$$ = 3 \times 2^4 = 48$ pts
Making tile $2^n$$ = (n-1)2^n$ points.
Making the max tile $2^{17}$$ = 16 \times 2^{17} = 2,097,152$ points. You would need to spawn 65,536 2 tiles to make a single 131,072 tile, which, at 1 legal move per second, would take 18.2 hours.
That's only making the max tile. Now we still need to fill the rest of the board. (Note: combining times are correct, as when you merge two tiles together, you spawn a 2 at the same time)
- Next tile $2^{16}$$ = 983,040$ points ($2^{15}$ tiles or $9.1$ hours)
- $2^{15}$$ = 458,752$ points ($2^{14}$ tiles or $4.55$ hours)
- $2^{14}$$ = 212,992$ points ($2^{13}$ tiles or $2.27$ hours)
- $2^{13}$$ = 98,304$ points ($2^{12}$ tiles or $1.13$ hours)
- $2^{12}$$ = 45,056$ points ($2^{11}$ tiles or $34$ minutes)
- $2^{11}$$ = 20,480$ points ($2^{10}$ tiles or $17$ minutes)
- $2^{10}$$ = 9216$ points ($512$ tiles or $8.5$ minutes)
- $512$$ = 4096$ points ($256$ tiles or $4.3$ minutes)
- $256$$ = 1792$ points ($128$ tiles or $2.1$ minutes)
- $128$$ = 768$ points ($64$ tiles or $64$ seconds)
- $64$$ = 320$ points ($32$ tiles or $32$ seconds)
- $32$$ = 128$ points ($16$ tiles or $16$ seconds)
- $16$$ = 48$ points ($8$ tiles or $8$ seconds)
- $8$$ = 12$ points ($3$ tiles or $3$ seconds)(This space will be created by two 2 tiles, and the last 4 tile, so $-4$ points from the equation)
This fills up 15 of the 16 spaces on the board. We don't include the last tile, as it cannot merge with the 8.
Max points possible: $3,932,156$.
Max tiles spawned: $131,070$ ($+1$ for last tile, $-1$ for the 4)
Around 36.4 hours @ 1 move per second.
If you happen to miss out on the last 4 tile, your max score would be $1,835,008$, with $65,535$ ($+1$ for last tile) 2 tiles spawned, and $18.2$ hours @ 1 move per second.