As "information radiators" handwritten artifacts are way more powerful than standard computer generated ones. Because they are linked with a person, reflect a creation effort and are more human. Even more, the mind easily capture a draw sketch rather than perfectly shape forms.
Of course, for storage and distribution of that kind of drawings a digitized solution is used. My Agile team use often the whiteboard and markers. When a drawing iteration is complete, we take a snapshot with the iPhone. I also use whiteboard capture pro sometimes to make real whiteboard drawing more like a sketch. This way we can also have "versions" of a software architecture sketch. This pictures are posted on wikis or distributed on email.
My Kanban board contains only handwritten post-its. When a client needs a project update or some estimations I just take snapshot of the board and send it by email. Never receive a complain about the form of the information.
So it's a handwritten-to-digital solution. We use it because of human flavor and because of speed. No matter how good you are in PowerPoint or whatever, it's faster to draw some boxes and arrows with a marker. It doesn't matter that they are not perfect, don't care. The most important is the content, not the form.
Of course, there are some limits. Not everything worth to be handwritten but Agile PM may rely on some handwritten artifacts.