In other words what changes from Classical Latin definitely were mainstream by that time: vowels, consonants, regional divergences? I'm aware of certain changes, but not exactly timewise when these changes became popular and widespread, if earlier or later than the 600s CE.
EDIT: I say specifically in the 600s CE, because around that time was when the Roman (Byzantine) Empire supposedly made Greek it's main official language instead of Latin, and when the school systems in the former Western Roman Empire were deterioating due to the Lombard invasion in Italy, Moors in Spain, and the Merovingian Dynasty domination in France. It was also around this time period where the last classical scholars were writing (Isidor of Seville, Gregory of Tours, Pope Gregory the First).