We know that the elasticity of substitution is defined as $$ e=\frac{d \ln(x_2/x_1)}{d \ln(MRS_{12})}=\frac{\frac{d(x_2/x_1)}{x_2/x_1}}{\frac{d(MU_1/MU_2)}{MU_1/MU_2}} $$
When we compute ES for CES functions, MRS is function of $x_2/x_1$, so we can let $z=x_2/x_1$ and do the math easily.
But for other utility/production functions, such as quasilinear $u(x_1,x_2)=2x_1^{0.5}+x_2$, what am I supposed to do?
I believe ES will be depending on $(x_1,x_2)$. So maybe the question can be asked as "What is ES of $u(x_1,x_2)=2x_1^{0.5}+x_2$ at $(x_1,x_2)=(1,1)$?"