Metilcobalamină

Metilcobalamina (MeCbl) este una dintre formele active biologic ale vitaminei B12 (cobalamină).[4] Este utilizată ca supliment alimentar pentru a preveni deficitul de vitamina B12.[5][6]

Metilcobalamină
Identificare
Număr CAS13422-55-4[1] 
PubChem6436232 
DrugBank03614[2] 
UNIIBR1SN1JS2W[1] 
KEGGC06453 
ChEMBLCHEMBL1697757 
Cod ATCB03BA05 
SMILES
[CH3-].CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=N7)C=C8C(C(C(=N8)C(=C4[N-]5)C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[Co+3][3] 
InChI
InChI=InChI=1S/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2/t31-,34+,35+,36+,37-,41+,52+,53+,56+,57-,59+,60-,61-,62-;;/m0../s1 
Date chimice
FormulăC₆₃H₉₁CoN₁₃O₁₄P[3] 
Masă molară1.343,587801222 u.a.m. 

Note
  1. Global Substance Registration System, accesat în
  2. https://www.drugbank.ca/releases/latest#open-data, accesat în aprilie 2018 Lipsește sau este vid: |title= (ajutor)
  3. „Metilcobalamină”, PubChem
  4. Sil A, Kumar H, Mondal RD, Anand SS, Ghosal A, Datta A, Sawant SV, Kapatkar V, Kadhe G, Rao S (iulie 2018). „A randomized, open labeled study comparing the serum levels of cobalamin after three doses of 500 mcg vs. a single dose methylcobalamin of 1500 mcg in patients with peripheral neuropathy”. The Korean Journal of Pain. 31 (3): 183–190. doi:10.3344/kjp.2018.31.3.183. PMC 6037815 . PMID 30013732.
  5. „Methylcobalamin”. The American Society of Health-System Pharmacists. Accesat în .
  6. „Mecobalamin”. DrugBank - Canadian Institutes of Health Research. Accesat în .

Vezi și
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.