NADH dehidrogenază

NADPH dehidrogenaza (EC 1.6.99.3, nicotin adenin dinucleotid dehidrogenaza) este o enzimă care catalizează reacția de transformare a nicotinamid adenin dinucleotidului (NAD) de la forma sa redusă (NADH) la forma sa oxidată (NAD⁺). Membrii familiei NADH dehidrogenazelor și a analogilor sunt denumiți utilizând formatul NADH:acceptor oxidoreductază.[1][2][3][4]

Reacția chimică catalizată este reprezentată la modul general:

NADH + H⁺ + acceptor

NAD⁺ + acceptor redus

Note

Adachi K, Okuyama T (iunie 1972). „Study on the reduced pyridine nucleotide dehydrogenase of bovine erythrocytes. I. Crystallization and properties of the reduced pyridine nucleotide dehydrogenase of bovine erythrocytes”. Biochimica et Biophysica Acta (BBA) - Enzymology. 268 (3): 629–37. doi:10.1016/0005-2744(72)90266-5. PMID 4402556.
Hatefi, Y.; Ragan, C.I.; Galante, Y.M. (1985). „The enzymes and the enzyme complexes of the mitochondrial oxidative phosphorylation system”. În Martonosi, A. The Enzymes of Biological Membranes. 4 (ed. 2nd). New York: Plenum Press. pp. 1–70.
Hochstein LI, Dalton BP (aprilie 1973). „Studies of a halophilic NADH dehydrogenase. I. Purification and properties of the enzyme”. Biochimica et Biophysica Acta (BBA) - Enzymology. 302 (2): 216–28. doi:10.1016/0005-2744(73)90150-2. PMID 4144655.
Kaniuga Z (august 1963). „The transformation of mitochondrial NADH dehydrogenase into NADH: Cytochrome c oxidoreductase”. Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 73 (4): 550–64. doi:10.1016/0926-6569(63)90175-5. PMID 14074130.

Vezi și

Legături externe

NADH dehydrogenase la Medical Subject Headings (MeSH), de la Biblioteca Națională de Medicină din Statele Unite

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[1] Adachi K, Okuyama T (iunie 1972). „Study on the reduced pyridine nucleotide dehydrogenase of bovine erythrocytes. I. Crystallization and properties of the reduced pyridine nucleotide dehydrogenase of bovine erythrocytes”. Biochimica et Biophysica Acta (BBA) - Enzymology. 268 (3): 629–37. doi:10.1016/0005-2744(72)90266-5. PMID 4402556.

[2] Hatefi, Y.; Ragan, C.I.; Galante, Y.M. (1985). „The enzymes and the enzyme complexes of the mitochondrial oxidative phosphorylation system”. În Martonosi, A. The Enzymes of Biological Membranes. 4 (ed. 2nd). New York: Plenum Press. pp. 1–70.

[3] Hochstein LI, Dalton BP (aprilie 1973). „Studies of a halophilic NADH dehydrogenase. I. Purification and properties of the enzyme”. Biochimica et Biophysica Acta (BBA) - Enzymology. 302 (2): 216–28. doi:10.1016/0005-2744(73)90150-2. PMID 4144655.

[4] Kaniuga Z (august 1963). „The transformation of mitochondrial NADH dehydrogenase into NADH: Cytochrome c oxidoreductase”. Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 73 (4): 550–64. doi:10.1016/0926-6569(63)90175-5. PMID 14074130.