< Bazedoxifene

Bazedoxifene/conjugated estrogens

Bazedoxifene/conjugated estrogens
Combination of
BazedoxifeneSelective estrogen receptor modulator
Conjugated estrogensEstrogen
Clinical data
Trade namesDuavee, Duavive
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa614004
License data
Pregnancy
category
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • None
KEGG

Bazedoxifene/conjugated estrogens, sold under the brand name Duavee among others, is a fixed-dose combination medication for the treatment of menopause symptoms and postmenopausal osteoporosis.[3][5][6] It contains the selective estrogen receptor modulator bazedoxifene and conjugated estrogens.[3] It is taken by mouth.[3]

The combination was approved for medical use in the United States in October 2013,[7] and in the European Union in December 2014.[4]

See also

References

  1. ↑ "Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy". Drugs.com. 16 February 2019. Retrieved 23 June 2020.
  2. ↑ "Duavive Product information". Health Canada. 9 June 2023. Retrieved 17 February 2025.
  3. 1 2 3 4 "Duavee- conjugated estrogens/bazedoxifene tablet, film coated". DailyMed. 16 July 2021. Retrieved 21 February 2022.
  4. 1 2 "Duavive EPAR". European Medicines Agency (EMA). Retrieved 10 June 2020.
  5. ↑ Palacios S, Mejía Ríos A (February 2015). "Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women". Drugs of Today. 51 (2): 107–16. doi:10.1358/dot.2015.51.2.2281023. PMID 25756066.
  6. ↑ Lello S, Capozzi A, Scambia G (2017). "The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause". International Journal of Endocrinology. 2017: 5064725. doi:10.1155/2017/5064725. PMC 5735652. PMID 29358948.
  7. ↑ "Drug Approval Package: Duavee (conjugated estrogens and bazedoxifene) NDA #022247". U.S. Food and Drug Administration (FDA). 7 October 2013. Retrieved 23 June 2020.


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